Angiomatous meningioma

Case contributed by A.Prof Frank Gaillard

Presentation

2 months memory loss and left upper limb weakness. CT showed a mass. MRI for further evaluation.

Patient Data

Age: 70 years
Gender: Male
Modality: MRI

A well defined frontal ovoid cystic mass with a thin slightly irregular rim is haemosiderin lined and contains a tiny blood fluid level. An irregularly shaped meningeal surface nodule appears suspended by thin septations that course through the cystic component to the posteromedioinferior walls that are likely to be contributing to the nodule's vascular supply. No prominent flow voids although minor flow voids are seen in the slightly nodular posteroinferior wall. The nodule intensely enhances and diffusion restricts apart from small internal cystic foci that are T2 hyperintense and T2 FLAIR/T1 hypointense. The CT reported second nodule is thought to reflect the slightly irregular rim rather than a real 2nd nodule. Although susceptibility from the haemosiderin affects the DWI sequence, minor peripheral diffusion restriction is also suspected. Minor adjacent smooth dural enhancement laterally with "dural tail", with possible CSF cleft.

Moderate surrounding vasogenic oedema. Moderate mass effect, with midline shift of 1 cm to the left. Both frontal horns distorted. No definite hydrocephalus. No second mass lesion. T2 hyperintensities scattered throughout the supratentorial white matter in keeping with small vessel ischaemic change.

Conclusion

Solitary right frontal cystic neoplasm with a pial surface nodule and minor internal haemorrhage. Dural tail with CSF cleft raises the possibility of this being extra-axial rather than intra-axial. If extra-axial, a variant meningioma would be most likely (e.g. cystic). If intra-axial, then combined demographic/imaging appearance does not particularly fit ?cystic GBM ?cystic metastasis ?primary cystic neoplasm.

Case Discussion

The patient went on to have surgery.

Histology

MICROSCOPIC DESCRIPTION: Sections of the brain tumour show features of a moderately cellular angiomatous meningioma with attached dura. The tumour forms scattered whorls with many blood vessels of varying sizes in the background, along with focal microcystic change. The tumour cells show occasional nuclear enlargement with prominent nucleoli. Mitoses are inconspicuous. There is no necrosis. Sections oft he cyst wall contain meninges and an underlying layer of cerebral cortex. Scattered chronic inflammatory cells are identified, along with haemosiderin deposits. No tumour is seen in the cyst wall. There is no evidence of brain invasion. No atypical or malignant change is identified.

FINAL DIAGNOSIS: Angiomatous meningioma (WHO grade I).

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Case Information

rID: 42305
Case created: 15th Jan 2016
Last edited: 17th Jul 2016
Inclusion in quiz mode: Included

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