Apocrine metaplasia

Case contributed by Dr Matt A. Morgan

Presentation

Patient presented for routine screening.

Patient Data

Age: 50-55
Gender: Female

Images from a screening mammogram

mammography

The breast is heterogeneously dense, which may obscure small masses. Breast implant.

There are coarse heterogeneous calcifications in a linear distribution in the outer central region of the left breast in the anterior portion.

mammography

Redemonstration of the coarse heterogeneous calcifications in a linear distribution in the outer central region of the left breast in the anterior portion.

Case Discussion

FINAL PATHOLOGIC DIAGNOSIS: Benign breast tissue, apocrine metaplasia with calcifications.
Pathology Concordant
Recommendation: Return to screening mammogram.

Although coarse heterogeneous calcifications are suspicious, not all are cancer. In this situation, there was concern that the patient had developed ductal carcinoma in situ (DCIS) based on the mammographic appearance, but pathology revealed apocrine metaplasia, a nonproliferative lesion that is not at increased risk for cancer.

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