Aspergillosis and air crescent sign

Case contributed by A.Prof Frank Gaillard


History withheld (see discussion).

Patient Data

Age: 20 years
Gender: Female

Chest x-ray

PA chest x-ray demonstrates a rounded density in the right midzone with an air crescent


CT chest

CT of the chest demonstrates a nodule with peripheral ground glass opacity. The central component is retracting away from the rest of the region with the formation of an air crescent

Case Discussion

This patient is neutropaenic but has improving cell counts. The development of an air crescent sign in the setting of angioinvasive aspergillosis is a good prognostic sign, denoting separation of the infarcted core from host response / granulation tissue. 

This should not be confused with an aspergilloma which occurs in patients with normal immunity and represents colonisation by aspergillus of a previously existing cavity (most commonly TB). 

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Case information

rID: 14380
Published: 20th Jul 2011
Last edited: 13th Nov 2015
System: Chest
Inclusion in quiz mode: Included

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