Atypical meningioma with marked oedema

Case contributed by A.Prof Frank Gaillard

Presentation

Increasing headaches

MRI of the brain of an adult demonstrates a mass arising in the inferomedial aspect of the anterior cranial fossa. It is of heterogeneous signal intensity, but largely isointense to grey matter on T1 and hyperintense to brain on T2, and demonstrates homogeneous intense contrast enhancement. The mass appears to be extra-axial (note the CSF cleft seen on T2 weighted images), and is associated with marked cerebral vasogenic oedema. 

Case Discussion

The most likely diagnosis is that of an atypical meningioma, although a haemangiopericytoma or dural metastasis should also be considered.

The patient went on to have a craniotomy and excision.

Histology

Sections show meningioma, focally associated with thin rims of fibrous tissue and neutropil. The pattern is predominantly meningothelial. Focal infiltration by meningioma into brain tissue is identified. Mitotic activity is not elevated.

Final diagnosis: atypical meningioma (WHO grade 2).

Comment: This meningioma was designated as being atypical because of the focal infiltration into brain tissue.

 

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Case information

rID: 5273
Case created: 29th Dec 2008
Last edited: 12th Apr 2017
Inclusion in quiz mode: Included

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