Autoimmune hemolytic anemia

Case contributed by Bruno Di Muzio
Diagnosis almost certain

Presentation

Tachycardia, tachypnea, sore tongue, and jaundice.

Patient Data

Age: 35 years
Gender: Female

CT Abdomen and pelvis

ct

CT images demonstrating hepatosplenomegaly, signs of abdominal venous congestion, a small amount of ascites, enlarged kidneys (RK 13.3 cm and LK 13.8 cm). Incidental simple cyst in the liver. 

Case Discussion

This patient had a confirmed diagnosis of hemolysis:

  • elevated serum unconjugated bilirubin 
  • raised lactic dehydrogenase (LDH)
  • low red blood cells count with increased reticulocytosis

The imaging findings in the abdomen and pelvis CT are non-specific, but reflect the pathophysiology of a hemolytic anemia: 

  • hepatosplenomegaly
  • large kidneys: believed to be a result of increased renal blood volume from the anemia

 

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