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Autosomal dominant polycystic kidney disease

Case contributed by Mohammad Taghi Niknejad
Diagnosis certain

Presentation

Flank pain and palpable masses on physical exam.

Patient Data

Age: 35 years
Gender: Female

Both kidneys are markedly enlarged and contain numerous varying-sized cysts. Some of them are hyperdense inferring hemorrhagic contents. Additionally, a few focal wall calcifications and also tiny stones are evident between the cysts. 

There are also a few small cysts at the liver less than 15 mm. 

Case Discussion

Features on CT are compatible with autosomal dominant polycystic kidney disease which is a common hereditary form of adult cystic renal disease
The kidneys are normal at birth but by the age of 60 years, approximately 50% of patients have end-stage renal failure due to numerous parenchymal cysts formation. 

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