Autosomal dominant polycystic kidney disease

Case contributed by Mohammad Taghi Niknejad
Diagnosis certain


Work up for bilateral flank pain and fullness.

Patient Data

Age: 45 years
Gender: Male

Both kidneys are enlarged and contain numerous varying sized cysts less than 50 mm in diameter. Some of the cysts have hyperdense contents inferring hemorrhage. A 4 mm stone is noted in the mid portion of the right kidney. Focal calcification could be considered in the differential list.

Case Discussion

A typical case of autosomal dominant polycystic kidney disease (ADPKD) in 45 years patient with bilateral flank pain and fullness. ADPKD is a common hereditary form of adult cystic renal disease and by far the most common hereditary cause of end stage renal failure. There is no increased risk for renal cell carcinoma (RCC) unless the patient is undergoing prolonged dialysis, unlike in some other congenital cystic kidney diseases.

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