Autosomal dominant polycystic kidney disease with hepatic involvement

Case contributed by Dr Mohammad Taghi Niknejad


Abdominal discomfort.

Patient Data

Age: 47
Gender: Female

There are enlarged kidneys with numerous cysts. The liver also contains numerous cysts with different size. Several tiny cysts also is seen in peripheral zone of spleen parenchyma.

Case Discussion

Features are consistent with known autosomal dominant polycystic kidney disease (ADPKD), a hereditary form of adult cystic renal disease

Cysts in other organs in a patient with ADPKD :

  • liver: most common, 75% by age 60 years 
  • seminal vesicles: 60% by age 40 years 
  • prostate: 11%
  • pancreas: ~10%
  • spleen: ~5 %
  • ovaries
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Case information

rID: 32693
Published: 9th Dec 2014
Last edited: 14th Aug 2019
Inclusion in quiz mode: Included

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