Basal ganglia calcification - Down syndrome

Case contributed by Bahman Rasuli
Diagnosis almost certain

Presentation

Down syndrome with major depressive disorders.

Patient Data

Age: 30 years
Gender: Female

Bilateral globus pallidus dystrophic calcification.

Case Discussion

Basal ganglia calcification is common and is seen in approximately 1% of all CT scans of the brain. It is seen more frequently in older patients and is considered a normal incidental and idiopathic finding in an elderly patient but should be considered pathological in those younger than 40 years of age unless proved otherwise 1.

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