Basal ganglia T1 hyperintensity
Clinical picture raised a suspicion of encephalitis, so an MRI Brain study was done
MRI brain plain and contrast
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Bilateral symmetrical T1 hyperintense signals from globus pallidi not enhancing on post contrast study.
Lab parameters revealed an album - globulin reversal. Possibility of chronic liver disease was suggested to the clinician. Screening ultrasound abdomen revealed hepatic sonomorphology suggestive of chronic liver parenchymal changes.
Hence a diagnosis of hepatolenticular degeneration was given.
- Lai PH, Chen C, Liang HL et-al. Hyperintense basal ganglia on T1-weighted MR imaging. AJR Am J Roentgenol. 1999;172 (4): 1109-15. Pubmed citation