Behçet disease - CNS manifestations

Case contributed by Joshua Alan Goldwag
Diagnosis certain


Encephalopathy and recurrent orogenital ulcers

Patient Data

Age: 25 years
Gender: Male

There is patchy hyperintensity with mild expansion of the pons and ventral midbrain. There is asymmetric involvement of the right cerebral peduncle over the left. The high signal involves the right mesodiencephalic junction with extension into the white matter tracts. There is patchy associated enhancement.

Case Discussion

This case represents the typical appearance of the central nervous system manifestations in a patient with Behçet disease. The hyperintensity on T2/FLAIR within the pons, midbrain, and mesodiencephalic junction with patchy enhancement are typical in the appropriate clinical setting.

Co-Author: Daniel P. Gewolb, M.D.

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