Benign fibrous histiocytoma

Case contributed by Frank Gaillard

Radiograph of the pelvis showing a well-circumscribed osteolytic lesion in the left iliac bone; it is sharply marginated with a thin sclerotic rim and without any matrix calcifications.

World J Surg Oncol. 2004; 2: 38. 


a-d: MRI shows a mass originating from the ileum and extending into the soft tissues both anteromedially and posterolaterally. In T1-weighted sequences the mass is isointense with muscle (a). It enhances after administration of gadolinium (b, c). In fat-suppressed T2-weighted sequences it has high signal intensity (d).

World J Surg Oncol. 2004; 2: 38.


Gross and microscopic pathology of benign fibrous histiocytoma. 

Macroscopic view of the resection specimen in transverse orientation. Large yellow osteodestructive tumor originating from iliac bone and with extensive extraosseous parts. Invasion of massa lateralis of sacral bone. Sharp borders between tumor and bone are indicative of a slow-growing neoplasm.

Histology of the resection specimen. Spindle tumor cells admixed with some multinucleated giant cells (left) and foamy macrophages (middle) and cholesterol clefts (right). (Hematoxyllin and Eosin x)

World J Surg Oncol. 2004; 2: 38. 

Case Discussion

These images are from: Niemeyer Philipp, Karl Ludwig, Mathias Werner et al. “Reconstruction of the pelvic ring using an autologous free non-vascularized fibula graft in a patient with benign fibrous histiocytoma.” World Journal of Surgical Oncology 2 (2004): 38.

Original file:

Modifications: cropped

License: This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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