Benign nerve sheath tumor

Case contributed by A.Prof Frank Gaillard


Incidental occipital skull finding on CT for further investigation.

Patient Data

Age: 35 Years
Gender: Female

The outer table of the left occipital bone is thinned and the defect filled with high T2 signal material. Unfortunately the patient is allergic to contrast. 

No inner table breach or meningeal abnormality. 

Case Discussion

The patient went on to have surgery.


MICROSCOPIC DESCRIPTION: Sections show subcutaneous tissue containing a non-encapsulated ill defined spindle cell tumor composed of short fascicles. Tumor cells contain scant eosinophilic cytoplasm and wavy nuclei. Scattered mast cells are present. No epidermis is present. No atypia or mitoses are seen. There is no evidence of malignancy. Immunohistochemically tumor cells stain: S100+, CD34-, SMA- and Factor XIIIa-.

FINAL DIAGNOSIS: Benign nerve sheath tumor.

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Case information

rID: 41944
Published: 28th Apr 2016
Last edited: 28th Apr 2016
Inclusion in quiz mode: Excluded

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