Binswanger disease

Case contributed by Abhinav Ranwaka
Diagnosis almost certain

Presentation

Dementia

Patient Data

Age: 75 years
Gender: Female

Binswanger disease

mri

There are marked confluent symmetrical T2 hyperintensities in bilateral periventricular and bilateral centrum semiovale with sparing of subcortical U fibers, representing chronic ischemic changes. Some small foci of blooming are noted on gradient sequence.

A small old hematoma is noted in the left thalamus.

Chronic lacunar infarcts are noted in the bilateral gangliocapsular regions.

Generalized age-related corticocerebral atrophy is seen.

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