Bisphosphonate-related osteonecrosis of the jaw

Case contributed by Dr Safwat Mohammad Almoghazy


A case of metastatic breast cancer to the bone on hormonal treatment with a bisphosphonate. The patient presented with suspected osteonecrosis of the mandible for CT scan to assess nature of the osteonecrosis.

Patient Data

Age: 60 years
Gender: Female

Multiple dental implants are noted degrading images quality at corresponding levels.

An osteolytic lesion seen in the right mandibular body with inner and outer cortical breaking with sequestrum bone within and evidence of tooth extraction compared to the previous study (provided ) with soft tissue component is seen suggestive of osteonecrosis rather than metastasis or osteomyelitis.

No other and similar suspicious lesions seen in the visualized bones.


Two years prior

Previous CT neck shows no lesion in the jaw.

Case Discussion

This case demonstrates typical case and complication of bisphosphonate osteonecrosis. 

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Case information

rID: 54147
Published: 2nd Jul 2017
Last edited: 14th Aug 2019
Inclusion in quiz mode: Excluded

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