Bladder papillary urothelial carcinoma

Case contributed by Bruno Di Muzio
Diagnosis certain

Presentation

Hematuria.

Patient Data

Age: 85 years
Gender: Male

CT IVP

ct

Solid enhancing mass arising from the right posterior bladder wall above the level of the right vesicoureteral junction and, although it has a bulging of the external bladder contour, does not extend into the surrounding fat planes. No enlarged lymph nodes seen, only a single 7.0 mm lymph node adjacent to the right common iliac vessels. The kidneys are normal in appearance, with no calculi, or hydronephrosis. There is a 4.0 cm cortical cyst in the right middle third that shows a few thin septations and calcifications (Bosniak II). The collecting systems are unremarkable, with no filling defects or strictures are identified. The remainder imaged solid and hollow abdominal viscera are normal in appearances. 

Case Discussion

Imaging features are consistent with a bladder tumor, most likely a transitional cell carcinoma

The patient was submitted to a transurethral resection of the bladder tumor (TURBT). 

MICROSCOPIC DESCRIPTION: The bladder biopsy shows features of high grade papillary urothelial carcinoma. The tumor comprises papillae and nests. The tumor cells have enlarged hyperchromatic nuclei and conspicuous nucleoli. Scattered mitoses are present. There is no evidence of lamina propria invasion. Lymphovascular invasion is not seen. Muscularis propria is identified in the biopsy and there is no evidence of muscle invasion.

DIAGNOSIS: TURBT: Non-invasive high grade papillary urothelial carcinoma.

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