Brain metastasis in malignant melanoma

Case contributed by Likhith Niranjanamurthy
Diagnosis almost certain

Presentation

Headache, weakness. Known case of malignant melanoma.

Patient Data

Age: 70 years
Gender: Male

Multiple altered signal intensity hemorrhagic lesions showing T1 W hyperintensity, blooming on SWI sequence are seen in supra and infratentorial compartment with mild perilesional edema. The lesions show enhancement as seen on post-contrast subtraction images.

Case Discussion

Malignant melanoma brain metastases are typically solitary, making them the third most frequent form of brain involvement after breast and lung cancer. Only about 5% of the cases have more than five metastatic brain lesions.

On T1-weighted images, brain metastasis typically appears hyperintense, while on T2-weighted images, it typically appears hypo intense, with the hemorrhagic component of the lesion having a greater influence than melanin. The SWI sequence facilitates the identification, evaluation, and characterization of the malignant melanoma metastasis subtypes.

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