Brainstem glioma

Case contributed by Bahman Rasuli
Diagnosis certain

Presentation

Headache, dizziness, and vertigo.

Patient Data

Age: 50 years
Gender: Female
mri

There is a 20*25*30 mm abnormal signal ( high on T2/FLAIR )  mildly expansile solid lesion involving the brain stem with extension to the right cerebral peduncle that shows faint enhancement after contrast injection.

The mass causes mild effacement on the aqueduct canal causing triventricular (lateral and third ventricles) hydrocephaly. 

High signal foci in T2/ FLAIR sequences at subcortical and periventricular white matter of both cerebral hemispheres depicts microvascular ischemic events.

Case Discussion

The mass was biopsied and histopathologic examinations revealed:

Microscopic: Sections show blood clots and embedded neoplastic tissue fragments with fibrillary background and low cellularity having uneven distribution.

Diagnosis: Astrocytoma(WHO grade I-II)

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