Breast calcifications (BI-RADS 4)

Case contributed by Mohammadtaghi Niknejad
Diagnosis almost certain


First screening mammography of a 40 YO female without familial history of breast cancer.

Patient Data

Age: 40 years
Gender: Female

Amorphous and fine pleomorphic calcifications are seen in a segmental distribution in the central lateral part of the right breast. (BI-RADS 4)

Stereotactic biopsy specimens


A mammography-guided stereotactic core needle biopsy was performed for the suspicious segmental calcifications of the right breast, and a specimen radiograph showed several pieces of specimens with multiple isolated calcification foci.

Case Discussion

Histopathology evaluation of the stereotactic biopsy specimens confirmed comedo-type ductal carcinoma in situ (DCIS), a high-grade subtype of ductal carcinoma in situ (DCIS).

It should be reminded that up to 25% of DCIS revealed on core biopsy may have invasive breast carcinoma following surgical excision.

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