Breast cancer pseudocirrhosis after chemotherapy

Case contributed by Michael P Hartung
Diagnosis certain


Breast cancer.

Patient Data

Age: 45

Staging exam.


Right breast mass. 

Numerous hepatic metastases of various sizes. Infiltrative appearance in the right hepatic lobe. 

6 months after chemotherapy.


New hepatic volume loss, capsular retraction, and diffusely nodular appearance with low attenuation bands branching throughout the liver. Hepatic masses have largely resolved. 

Case Discussion

Discretely round and infiltrative metastases throughout the liver with treatment response after chemotherapy resulting in the typical appearance of pseudocirrhosis. 

Note that pseudocirrhosis can indicate both regression of tumor after treatment (as in this case), or progression of fibrosis surrounding infiltrative hepatic metastases. Despite the treatment response in this case, patients with pseudocirrhosis are at risk for developing portal hypertension and can progress to liver failure.1

Pseudocirrhosis playlist

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