Breast cancer response patterns during neoadjuvant chemotherapy
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Breast MR imaging is the most sensitive modality for breast cancer detection and is the most accurate imaging modality for assessment of tumor response to neoadjuvant therapy.
The Union for International Cancer Control (UICC) response patterns is the most used method to assess breast cancer response to neoadjuvant treatment.
These patterns are as follows:
No changes were observed in the tumor size
MINOR PARTIAL RESPONSE
Tumor size reduction < 50 %
MAJOR PARTIAL RESPONSE
Tumor size reduction > 50 %
No radiological residual tumor
- Fowler, A. M., Mankoff, D. A., & Joe, B. N. (2017). Imaging neoadjuvant therapy response in breast cancer. Radiology, 285(2), 358–375. https://doi.org/10.1148/radiol.201717018
- Wittekind C, Hutter R, Greene FL, Klimpfinger M, Sobin LH. Union for International Cancer Control (UICC). TNM Atlas. 5th ed. Heidelberg, Germany: Springer; 2005