Breast lymphoma

Presentation

Palpable mass in the left breast.

Patient Data

Age: 60 years
Gender: Female

A. Mediolateral oblique mammogram of the left breast shows an extremely dense, type D (ACR), and a high-density mass with obscured and indistinct margins, located in the upper internal quadrant, posterior third.

B. Craniocaudal mammogram of the left breast shows a high-density mass with obscured margins.

Hypoechoic heterogeneous irregular mass with indistinct margins, anechoic areas, posterior shadow, and internal vascularity.

Core biopsy of the solid irregular heterogeneous mass. 

FDG PET-CT of the left breast located in the upper internal quadrant shows focal hypermetabolism.

Compare with the CT simple, shows a homogenous mass.

Case Discussion

Diagnosis: 

LARGE CELL DIFFUSE NON-HODGKIN LYMPHOMA.

Immunohistochemistry: 

CD 20 Positive

CD 3 Positive

CKAE/AE3 Negative

CKAE/AE3 Negative

CD3 POSITIVE IN REACTIVE LYMPHOCYTES

Breast lymphoma is hematologic cancer and a rare tumor and represents 0.04- 0.7% of all breast. Represents 0.38-0.7% of all non-Hodgkin lymphomas.

This cancer is very aggressive and affects old women 60-85 years. 

Are divided into primary and secondary. The first has many subtypes and the most common is a diffuse large B cell lymphoma approximately 45-79% and Burkitt lymphoma is associated with people VIH +, pregnancies, and women in lactation, and represents only 10%. 

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