Bronchiolotis obliterans

Case contributed by Bruno Di Muzio
Diagnosis almost certain

Presentation

Bilateral lung transplant for cystic fibrosis 16 months ago.

Patient Data

Age: adolescent
Gender: Unknown

Chest

ct

Diffuse lung parenchyma mosaicism due to extensive air-trapping and associated mild bronchiectasis. A few anterior bands of atelectasis, with the lungs and pleural spaces otherwise clear. The bronchial anastomosis are patent. No mediastinal lymphadenopathy. PEG tube partially imaged within the superior abdomen. No suspicious osseous lesions.

Case Discussion

Typical features of bronchiolitis obliterans syndrome, which is the most common phenotype of chronic lung allograft dysfunction (CLAD)

Given the lung function deterioration clinically and on lung function tests, this patient was put on the list for a new transplant. 

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