Burkitt's lymphoma of the orbit: pre and post chemotherapy

Case contributed by Dr Arthur Daire

Presentation

This young boy with histologicaly proven Burkitt's lymphoma. Presented initially with pain and proptosis of the right eye and headaches for a 2 month duration

Patient Data

Age: 5
Gender: Male

This baseline study demonstrates the extent of the multiple tumour  prior to chemotherapy in the base of skull extending into the sphenoid bone and superiorly in the lateral aspect of the left globe (extraconal), inseparable from the lateral rectus muscle.This is causing severe proptosis of the right globe.In addition, there is another carvarial mass lesion in the right occipital region, which extends internally and seems to breach the dura.

This study was done at exactly 2 months after the initial study demonstrated complete resolution of all the masses that were seen on the initial scan.

Case Discussion

Burkitt's lymphoma  is a type of non-Hodgkin lymphoma, more common in the so called "Burkitt's lymphoma belt" where there is high prevalence of malaria. It has also been associated with Epstein-Barr virus. This type of lymphoma responds very well to chemotherapy alone(Cyclophosphamide, Doxorubicin, Vincristine, Methotrexate and predenisolone in this case)

This case demonstrated  the good response  of Burkitts lymphoma  to chemotherapy on imaging.

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Case information

rID: 31214
Case created: 24th Sep 2014
Last edited: 5th Oct 2015
Inclusion in quiz mode: Included

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