CADASIL with microbleeds

Case contributed by Yves Leonard Voss


Genetically confirmed CADASIL Syndrome.

Patient Data

Age: 30 years
Gender: Female

Leukoencephalopathy of the periventricular and deep frontoparietal white matter, anterior temporal pole, and external capsule (best seen on FLAIR). SWI shows deep cerebral microbleeds, resembling the pattern seen in hypertensive microangiopathy.

Case Discussion

White matter changes and microbleeds typical for CADASIL (especially in a young patient like this without arterial hypertension). 

Typical leukoencephalopathy and cerebral microbleed distribution for CADASIL.

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