Calvarial doughnut lesion

Q: What is the definition of calvarial doughnut lesions? show answer

A: Calvarial doughnut lesions consist of one or more radiolucent ring-like defects, with surrounding sclerotic halo, which may occur in any part of the skull, of unknown etiology.

Q: Which are the principal differential diagnosis of calvarial doughnut lesions? show answer

A: The principal differential diagnosis of calvarial doughnut lesions is a venous lake, intradiploic epidermoid cyst, hemangioma, eosinophilic granuloma, fibrous dysplasia.

Q: How are the clinical manifestations of calvarial doughnut lesions? show answer

A: Calvarial doughnut lesions may be isolated findings detected as an incidental asymptomatic finding, and with no clinical significance. Occasionally this entity is related to familial multiple calvarial doughnut lesions and forms part of a rare autosomal dominantly inherited syndrome. This syndrome characterizes by calvarial doughnut lesions, many fractures, dental caries, undeveloped teeth, and elevated serum ALP level. In some patients with multiple calvarial doughnut lesions, the only clinical manifestation is a "lumpy" skull.

Q: What are the radiographic configurations of calvarial doughnut lesions? show answer

A: The doughnut lesions occur in any portion of the skull and present a ring-like aspect, which may be divided into two groups by their radiographic configuration. The Group I presents as a small, well-defined area of radiolucency, surrounded by a dense sclerotic bone. The lesions in Group II tend to be larger, and the radiolucency and the sclerotic margins less regular. Lesions of both groups may contain irregular areas of the density of varying sizes within the central areas of radiolucency.

Q: How is the treatment of calvarial doughnut lesions? show answer

A: There is currently no evidence for intervention or surgical management of the disorder.