Castleman disease with fibrous pseudotumor in the abdomen

Case contributed by Michael P Hartung
Diagnosis almost certain

Presentation

Abdominal discomfort.

Patient Data

Age: 45 years
Gender: Female

Partially calcified right lower abdominal soft tissue mass. No other suspicious findings. 

Case Discussion

Excisional biopsy confirmed hyaline-vascular type of Castleman disease with calcifying fibrous pseudotumor. 

Castleman disease is a non-neoplastic, non-clonal lymph node hyperplasia which can be idiopathic or associated with HIV, lymphoma, POEMS and other disorders. It commonly presents as avidly-enhancing adenopathy. Most cases (90%) are hyaline vascular, which occurs in younger patients, is unicentric, asymptomatic, and follows a benign course.

 

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