Central giant cell granuloma

Case contributed by Travis Fahrenhorst-Jones
Diagnosis almost certain


Previously characterized giant cell granuloma of the mandible for surveillance.

Patient Data

Age: 25 years
Gender: Female

Expansile multiloculated lucent lesion of the left mandibular ramus with a narrow zone of transition and expansion medially of the cortex. No aggressive features such as periostitis present. No new suspicious osseous lesion demonstrated. The paranasal sinuses and mastoid air cells are well pneumatized.

Case Discussion

Central giant cell granulomas are benign destructive intraosseous lesions most commonly affecting the mandible. The most common age group at presentation is patients under the age of 30 with a female predilection 1. Due to the slow-growing nature of the lesion, delay in diagnosis is not uncommon 2.

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