Cerebral amyloid angiopathy

Case contributed by Ammar Haouimi


Memory disturbance.

Patient Data

Age: 70 years
Gender: Male

Multiple foci of susceptibility artifact are noted along the surface of the cerebellar/cerebral hemispheres and subarachnoid space of the cerebral convexity suggestive of micro-hemorrhages. Note sparing of the basal ganglia and pons.

White matter T2/FLAIR hyperintense lesions mainly involve the periventricular regions and centrum semiovale (chronic small vessel ischemia).

Case Discussion

MRI features of multiple areas of susceptibility artifact in the cerebellum and cerebral hemispheres (micro hemorrhage) with convexity subarachnoid hemorrhage suggest probable cerebral amyloid angiopathy.

The main differential diagnosis is the hypertensive microangiopathy which is characterized by

  • hemorrhages, including micro hemorrhages, typically located in basal ganglia, pons and cerebellum
  • not associated with subarachnoid hemorrhage or superficial siderosis

How to use cases

You can use Radiopaedia cases in a variety of ways to help you learn and teach.

Creating your own cases is easy.

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.