Cerebral amyloid angiopathy related inflammation

Case contributed by Tahir
Diagnosis probable

Presentation

Presented to the Emergency Department with acute onset headache and “talking gibberish” at the bank.

Patient Data

Age: 55 years
Gender: Female

CT shows left temporal white matter hypodensity.

Swelling left temporal lobe and diffuse hyperintensity in white matter on FLAIR. Microhemorrhages in medial left temporal lobe on T2* image provide a clue to the etiology. No enhancement on contrast enhanced 3D SPGR. 

One month follow up

mri

Marked improvement is noted on one month follow up scan after brain biopsy and treatment with prednisolone.

Case Discussion

Cerebral amyloid angiopathy (CAA) is a cerebrovascular disorder that tends to manifest in normotensive elderly patients. Occasionally localized inflammation can be seen, known as cerebral amyloid angiopathy-related inflammation

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