Cerebral amyloid angiopathy-related inflammation (CAA-RI)

Case contributed by Yves Leonard Voss
Diagnosis probable

Presentation

Progressive cognitive impairment, apraxia, and aphasia for a few weeks.

Patient Data

Age: 70 years
Gender: Female

Left occipital cortical and subcortical FLAIR hyperintensity and grouped microbleeds. Very subtle leptomeningeal enhancement. No restricted diffusion. 

A few other microbleeds are found in the left temporal lobe. 

Case Discussion

Clinical history of progressive cognitive decline over a few weeks and asymmetrically grouped cerebral microbleeds with focal corticosubcortical FLAIR hyperintensity, untypical for stroke and without restricted diffusion, we suspected cerebral amyloid angiopathy related inflammation (CAA-RI). 

Probatory corticoid treatment resolved FLAIR changes and the patient returned to near normal cognitive function. 

How to use cases

You can use Radiopaedia cases in a variety of ways to help you learn and teach.

Creating your own cases is easy.

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.