Cerebral fat embolism

Case contributed by Dr Kauv Paul

Presentation

Sickle cell patient. History of bone infarct.

Patient Data

Age: 30 years
Gender: Female
MRI

Diffuse and tiny foci of susceptibility artifact. No restricted diffusion. 

Case Discussion

Very important small regions of susceptibility artifact (more than 100) lead to the diagnosis of cerebral fat embolism. Especially with a history of bone infarct which is the etiology of embolism rather than bone fracture as usual. This patient had sickle cell disease with cerebral fat embolism that should evoke bone infarct.

Those lesions are visible in T2*, but better with SWI

Differentials are amyloid angiopathy or chronic hypertensive encephalopathy but those hemorrhagic lesions are bigger and fewer.

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