Presentation
Headache and vomiting. History of lung mass.
Patient Data
Age: 40 years
Gender: Female
From the case:
Cerebral metastases - lung cancer
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Numerous abnormal signal intraparenchymal enhancing lesions are seen supra- and infratentorially.
Some of the lesions show areas of internal T1 hyperintensities which could be due to hemorrhage.
Case Discussion
The patient already had a diagnosis of pathologically-proven lung adenocarcinoma from a biopsy six months ago, detailed below. Thus, cerebral metastases is the most likely diagnosis.
Microscopy: slides demonstrate infiltration of malignant neoplastic tissue composed of cells with high N/C ratio, pleomorphic hyperchromatic nuclei which cover alveolar spaces and also focally arrange occasionally in gland-like structure. There is also necrosis and vascular invasion.
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