Presentation
Headache and vomiting. History of lung mass.
Patient Data
Age: 40 years
Gender: Female
From the case:
Cerebral metastases - lung cancer
{"current_user":null,"step_through_annotations":true,"access":{"can_edit":false,"can_download":true,"can_toggle_annotations":true,"can_feature":false,"can_examine_pipeline_reports":false,"can_pin":false},"extraPropsURL":"/studies/83125/annotated_viewer_json?iframe=true\u0026lang=us"}
Numerous abnormal signal intraparenchymal enhancing lesions are seen supra- and infratentorially.
Some of the lesions show areas of internal T1 hyperintensities which could be due to hemorrhage.
Case Discussion
The patient already had a diagnosis of pathologically-proven lung adenocarcinoma from a biopsy six months ago, detailed below. Thus, cerebral metastases is the most likely diagnosis.
Microscopy: slides demonstrate infiltration of malignant neoplastic tissue composed of cells with high N/C ratio, pleomorphic hyperchromatic nuclei which cover alveolar spaces and also focally arrange occasionally in gland-like structure. There is also necrosis and vascular invasion.