Cerebral metastases - lung cancer

Case contributed by Dr Bahman Rasuli


Headache and vomiting. History of lung mass.

Patient Data

Age: 40 years
Gender: Female

Numerous abnormal signal intraparenchymal enhancing lesions are seen supra- and infratentorially.

Some of the lesions show areas of internal T1 hyperintensities which could be due to hemorrhage.

Case Discussion

The patient already had a diagnosis of pathologically-proven lung adenocarcinoma from a biopsy six months ago, detailed below. Thus, cerebral metastases is the most likely diagnosis. 

Microscopy: slides demonstrate infiltration of malignant neoplastic tissue composed of cells with high N/C ratio, pleomorphic hyperchromatic nuclei which cover alveolar spaces and also focally arrange occasionally in gland-like structure. There is also necrosis and vascular invasion.

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Case information

rID: 72568
Published: 2nd Dec 2019
Last edited: 3rd Dec 2019
Inclusion in quiz mode: Included
Institution: Jame Jam Imaging Center

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