Cerebral metastases - lung cancer
Headache and vomiting. History of lung mass.
Loading Stack -
0 images remaining
Numerous abnormal signal intraparenchymal enhancing lesions are seen supra- and infratentorially.
Some of the lesions show areas of internal T1 hyperintensities which could be due to hemorrhage.
The patient already had a diagnosis of pathologically-proven lung adenocarcinoma from a biopsy six months ago, detailed below. Thus, cerebral metastases is the most likely diagnosis.
Microscopy: slides demonstrate infiltration of malignant neoplastic tissue composed of cells with high N/C ratio, pleomorphic hyperchromatic nuclei which cover alveolar spaces and also focally arrange occasionally in gland-like structure. There is also necrosis and vascular invasion.