Cerebral small vessel disease (illustration)

Case contributed by Rohit Sharma
Diagnosis not applicable

This illustration depicts and contrasts the radiographic features of two common causes of cerebral small vessel disease.

  • cerebral amyloid angiopathy (left of diagram)

    • cortical microbleeds

    • cortical superficial siderosis

    • convexity (convexal) subarachnoid hemorrhage (cSAH)

    • enlarged perivascular spaces of the centrum semiovale

    • white matter hyperintensities (WMH): subcortical, multiple spot pattern, occipital predominance

  • sporadic non-amyloid small vessel disease ("hypertensive arteriopathy") (right of diagram)

    • deep and subcortical microbleeds

    • enlarged perivascular spaces of the basal ganglia

    • deep lacunes

    • white matter hyperintensities (WMH): deep, more likely to be confluent, periventricular and peri-basal ganglia predominance

Case Discussion

Attribution and copyright: this illustration was created by Dr Andreas Charidimou, and has been faithfully reproduced and uploaded to Radiopaedia.org with his permission. Dr Charidimou owns the copyright to this illustration. In citing this image, please use Dr Charidimou's name as the author of this case. The original illustration can be found here.

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