Chondrosarcoma - nasal septum

Case contributed by Frank Gaillard
Diagnosis certain


Epistaxis; Difficulty in breathing; Mass per examination in nasal cavity.

Patient Data

Age: 50 years
Gender: Male

Bony erosion and destruction of posterior nasal septum with a soft tissue attenuation mass epicentered at septum. Some stippled calcific specks noted in lesion.

Case Discussion

The patient went on to have a resection.


The resected tumor shows variable cellularity and mild nuclear pleomorphism. Some of the fragments contain bone and there is a strong suggestion of permeative growth in these fragments. There are multiple foci of chondrocyte necrosis present. The appearance is that of a low-grade chondroid neoplasm, consistent with low-grade chondrosarcoma.

FINAL DIAGNOSIS: low-grade chondroid neoplasm, consistent with chondrosarcoma grade 1.

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