Case contributed by A.Prof Frank Gaillard

Clival destruction with a large soft tissue component extending anteriorly and attenuating the airway


Reformated images illustrate the extensive destruction of the clivus and the soft tissue component

Case Discussion

Nasopharynx, biopsy: Chordoma.

consists of myxoid tissue containing polygonal cells with prominent cell borders and pink cytoplasm. Some of the cells are vacuolated. Immunohistochemistry has been carried out and this shows that the tumor cells stain strongly with both epithelial markers (pan-keratin, cam5.2, EMA) and with S100, typical of chordoma.

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Case information

rID: 5200
Case created: 16th Dec 2008
Last edited: 19th Oct 2017
Inclusion in quiz mode: Included

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