CMV duodenitis: histology

Case contributed by Dr Andrew Ryan

Presentation

Dyspepsia. Past history of AML with transplant.

Patient Data

Age: 55
Gender: Male
Pathology

The biopsies of the duodenum shows scattered enlarged cells containing both large intranuclear inclusions and basophilic (more purple) intracytoplasmic inclusions.

Case Discussion

While CMV viral inclusions can be seen in enterocytes, they are more commonly identified in endothelial cells or stromal cells. When prominent, enterocyte inclusions should raise the differential diagnosis of adenovirus infection however cells infected with adenovirus should show inclusions restricted to the nucleus and do not show 'cytomegaly' (cell enlargement).

PlayAdd to Share

Case information

rID: 27528
Case created: 6th Feb 2014
Last edited: 10th Sep 2016
Inclusion in quiz mode: Excluded

Updating… Please wait.
Loadinganimation

Alert accept

Error Unable to process the form. Check for errors and try again.

Alert accept Thank you for updating your details.