CNS lymphoma

Case contributed by Ryan Thibodeau
Diagnosis certain


History of large B-cell intraocular lymphoma. Increasingly severe headaches.

Patient Data

Age: 50 years
Gender: Male

There is expansile intermediate T2 signal mass within the medial left temporal lobe, which

CTA for surgical planning.


Redemonstration of an expansile lesion along the medial left temporal lobe. Additional lesions seen on MR are not visualized on this examination.

There is asymmetric prominence and increase in caliber of the left MCA vasculature, most noticeable within the M2 and M3 segments of the vasculature.

Case Discussion

This is a CNS lymphoma. The patient has a history of diffuse large B cell lymphoma. He was treated with several courses of rituximab, methotrexate, procarbazine, vincristine (R-MPV) and intraventricular rituximab.

Despite treatment, the patient had progressive right sided hemiataxia, dysarthria, and headaches. An MRI showed progression of right cerebellar lesion and concern for hydrocephalus due to ventricular involvement. He continued to have worsening mental status. He eventually expired due to complications related to therapy.

Jun Yang

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