Collecting duct carcinoma

Case contributed by Jose Rodriguez Vazquez
Diagnosis certain


Patient with a past medical history of benign prostatic hyperplasia status-post transurethral resection of the prostate and primary renal malignancy presents Oncology clinic for continued care.

Patient Data

Age: 70 years
Gender: Male

Non-contrast and renal excretory phase CT urogram images demonstrate incomplete duplication of the right kidney, best appreciated on 3D images. In the inferior pole moiety of the right kidney, there is a 3.7cm mixed expansile/infiltrative, isoattenuating, and hypoenhancing mass.

Case Discussion

Patient underwent right nephrectomy. Pathology revealed a collecting duct (Bellini) carcinoma.

Key points:

  • collecting duct carcinoma (CDC), also known as Bellini carcinoma, is a very rare renal cell carcinoma subtype

  • patients with CDC typically present with a flank mass and gross hematuria, similar to other renal malignancies

  • it typically affects patients in their mid 50's. It is thought to originate in the renal medullary pyramids along the distal segment of the collecting duct

  • its pattern of growth has been described as infiltrative, but are typically detected at an advanced stage and size, which makes it difficult to distinguish from other RCC subtypes

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