Congenital hypothyroidism - agenesis of thyroid gland
Citation, DOI, disclosures and case data
At the time the case was submitted for publication Yusra Sheikh had no recorded disclosures.View Yusra Sheikh's current disclosures
Elevated TSH at 100 µIU/mL. Free T4 <5.2 ng/dL ? agenesis of thyroid gland.
Loading Stack -
0 images remaining
14.8 MBq of Tc-99m pertechnetate was administered intravenously. Cobalt sternal notch marker noted.
There was no isotope uptake demonstrated in the cervical region or tongue base. In this clinical context, appearances are most likely to represent thyroid gland agenesis.
Congenital hypothyroidism is one of the preventable causes of neurodevelopmental retardation. Newborn screening for thyroid disease can lead to more rapid treatment of abnormal cases. The technetium-99m examination is important in differentiating thyroid agenesis, ectopic thyroid and dyshormonogenesis.