Presentation
Routine antenatal ultrasound with serial post natal follow up.
Patient Data
Antenatal scan at 29th wk gestation
Dilated occipital horns of lateral ventricles with parallel appearance of bilateral lateral ventricles.
Dilated occipital horns of lateral ventricles with parallel appearance of bilateral lateral ventricles. Absent corpus callosum in sagittal images. An interhemispheric cyst is also seen.
Dilated occipital horns of lateral ventricles with parallel appearance of bilateral lateral ventricles (racing car sign). Absent corpus callosum in sagittal images. An interhemispheric cyst is also seen.
Case Discussion
The corpus callosum is a major axonal commissure of the brain connecting the two cerebral hemispheres and providing communication between the cortical and subcortical neurons.
Corpus callosum agenesis results from failure of the callosal commissural fibers to cross the midline and form the major connection between the two cerebral hemispheres.
It may be complete or partial and may occur in isolation or in association with other CNS or systemic malformations.