Corpus callosum agenesis with interhemispheric cyst and subependymal heterotopia
Diagnosis almost certain
Presentation
Developmental delay. Abnormal antenatal ultrasound.
Patient Data
Age: 4 months
Gender: Female
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MRI sequences demonstrate:
- agenesis of the corpus callosum with parallel lateral ventricles, dilatation of the occipital horns (colpocephaly), high-riding 3rd ventricle, narrow frontal horns, absence of the cingulate sulcus, and widened mid-portion of the interhemispheric fissure
- well-defined interhemispheric cyst slightly hyperintense to the CSF on T1 and FLAIR, and isointense on T2 with no restricted diffusion
- subependymal grey matter heterotopia along the left ventricular margin
Case Discussion
MRI features of agenesis of the corpus callosum with interhemispheric cyst and subependymal heterotopia.