Corpus callosum lymphoma
Patient with known illness. Follow-up brain CT.
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There is a voluminous hyperdense mass involving splenium of the corpus callosum and a more subtle lesion in the right temporal uncus, with extensive edema associated. There is compression of the atriums.
The pathologic diagnosis was lymphoma which is usually hyperdense on CT; helpful in differentiating it from other malignancies.
The main differential diagnosis for a corpus callosal mass includes:
- lymphoma (PCNSL)
- glioblastoma multiforme (butterfly glioma)
- less frequently encountered
- tumefactive demyelination
- radiation necrosis
- evolving hemorrhage / contusion / infarct
Lipoma of the corpus callosum very rarely occurs, but the diagnosis is usually straight-forward since there is an obvious fat density.