Craniopharyngioma - papillary
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MRI of the brain demonstrates a mass in the suprasellar region which is variegated in both T1 and T2 signal, with regions of intrinsic high T1 signal, cystic areas and solid enhancing areas.
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This patient went on to have resection of the mass.
The tumour comprises solid islands, some with a fragmented and papillary outline, of well-differentiated squamous epithelium embedded in a densely collagenous and vascularised stroma, which shows patchy chronic inflammation. The tumour does not show a well-developed picket fence basal epithelial layer, and stellate reticulum-like areas and wet keratin are not identified. Focally, the tumour shows areas of haemorrhage, and there is one fragment showing haemorrhagic infarction. There is patchy infiltration by neutrophils.
DIAGNOSIS: Papillary craniopharyngioma, WHO grade 1.
This case demonstrates a common appearance of papillary craniopharyngioma.