Creutzfeldt-Jakob disease

Case contributed by Dr Maxime St-Amant

Presentation

Headaches & memory loss in a young patient.

Patient Data

Age: 45 years
Gender: Male
MRI

MRI shows subtle abnromal signal intensity in the basal ganglion, particularly evident within the caudate nucleus.

The basal ganglia are hyperintense on DWI (not shown, but hypointense on ADC) & slightly hyperintense on T2. As mentionned previously, this is more evident with regard to the caudate nucleus. There is no abnormal cortical signal or diffusion restriction. 

Case Discussion

There is a broad differential diagnosis for T2 basal ganglia hyperintensities.

However, the diagnosis of Creutzfeldt-Jakob was confirmed a few weeks after the MRI was done. DWI is the most sensitive sequence for this disease.

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Case information

rID: 18712
Case created: 19th Jul 2012
Last edited: 27th Jun 2017
Inclusion in quiz mode: Included

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