Crohn disease - comb sign

Case contributed by Mohamed Saber
Diagnosis certain

Presentation

A known case of Crohn's disease presented with acute abdominal pain.

Patient Data

Age: 10 years
Gender: Female
ct

CT study shows the following:

  • circumferential mural thickening of multiple loops of the distal ileum with mucosal hyperenhancement. These changes are more prominent at the terminal ileum where a significant mural thickening results in a stenotic lumen with subsequent upstream dilatation results in moderate dilatation of multiple distal ileal loops
  • associated congested mesenteric vessels are more prominent at the right iliac fossa resulting in a characteristic "Comb sign". The ileocolic- right colic arterial trunk appears hypertrophied
  • blurred mesenteric fat planes, multiple mesenteric lymph nodes, and mild intraperitoneal free fluid collection
  • all these changes are radiologically suggestive of an active attack of Crohn's disease
Annotated image

Yellow arrows point to the comb sign.

Case Discussion

Here is a case with typical CT findings of Crohn disease including the comb sign.

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