Crohn's disease

Case contributed by Ilya Lysach
Diagnosis certain

Presentation

The patient was sent on MR enterography after coloscopy revealed inflammatory reactions in the walls of the caecum (in the region of the ileocaecal angle). The colonoscope did not pass into the terminal ileum. A biopsy has taken place.

Patient Data

Age: 25 years
Gender: Male

MR enterography

mri

MR enterography with oral contrast using mannitol.

There is wall thickening (max thickness 10 mm, length of changes more than 80 mm) in the terminal ileum, ileocaecal zone and proximal caecum. In addition, the affected walls of the ileum restrict diffusion, indicating active inflammation.

The intestinal walls at this level are inflamed with reactive changes in the surrounding tissues, the mesentery, and the formation of an infiltrate in the ileocaecal angle, up to 42 mm in size. After injection of a contrast agent -  layered enhancement pattern. In the same area, lymph nodes up to 6 mm in size are traced.

The appearances are highly suggestive of Crohn's disease (severe activity).

Histology: tumour not found, inflammatory changes possibly associated with Crohn's disease.

Case Discussion

Тhickening of the wall ileum up to 10 mm with restricted diffusion, inflammatory mass, layered contrast enhancement pattern, is compatible with the histology of Crohn's disease.

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