CTA spot sign
90 minutes post onset left sided weakness
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Non-contrast CT (A) performed demonstrates a small right basal ganglia intracerebral haemorrhage. CTA source image demonstrates punctate focus of contrast enhancement within the haemorrhage that was discontinuous from adjacent vessels on multi-planar reformats, and not present on the pre-contrast image, the CTA 'spot sign', reflecting active, dynamic haemorrhage. Follow-up 24 hour non-contrast CT (C) demonstrates haematoma growth.
The CTA Spot sign is defined as unifocal or multifocal contrast enhancement within an intracerebral haemorrhage, discontinuous from adjacent normal or abnormal vessels and not present on pre-contrast imaging. It is an independent predictor of intracerebral hemorrhage growth and poor outcome.
- Wada R, Aviv RI, Fox AJ et-al. CT angiography "spot sign" predicts hematoma expansion in acute intracerebral hemorrhage. Stroke. 2007;38 (4): 1257-62. doi:10.1161/01.STR.0000259633.59404.f3 - Pubmed citation
- Demchuk AM, Dowlatshahi D, Rodriguez-Luna D et-al. Prediction of haematoma growth and outcome in patients with intracerebral haemorrhage using the CT-angiography spot sign (PREDICT): a prospective observational study. Lancet Neurol. 2012;11 (4): 307-14. doi:10.1016/S1474-4422(12)70038-8 - Pubmed citation